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Liothyronine is a medication that contains the active ingredient triiodothyronine (T3), which is a synthetic form of the thyroid hormone. It is primarily used to treat hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormone. Thyroid hormones play a crucial role in regulating various bodily functions, including metabolism, growth, and development. Liothyronine works by supplementing the deficient levels of thyroid hormone in the body. .