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Janumet is a brand name for a prescription medication that combines two active ingredients: sitagliptin and metformin. It is primarily used to manage blood sugar levels in individuals with type 2 diabetes. Sitagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the levels of incretin hormones in the body, which helps regulate blood sugar levels by stimulating insulin release and reducing the production of glucose by the liver.