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14.64$ per 100 tablets Guanfacine is a medication that belongs to the class of drugs known as alpha-2 adrenergic agonists. It is primarily used to treat attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. Guanfacine works by stimulating certain receptors in the brain known as alpha-2 adrenergic receptors. By activating these receptors, it helps regulate certain functions in the prefrontal cortex, which is involved in attention, impulse control, and behavior.