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16.85 rs, Glipizide is an oral medication that belongs to the class of drugs known as sulfonylureas. It is primarily used to lower blood sugar levels in individuals with type 2 diabetes. Glipizide works by stimulating the release of insulin from the pancreas and increasing the sensitivity of cells to insulin. Insulin is a hormone that helps regulate blood sugar levels by facilitating the uptake of glucose from the bloodstream into cells for energy.